Xiuli An, MD, PhD

An, Xiuli-cropped.jpg

Head, Laboratory of Membrane Biology
Associate Member, Lindsley F. Kimball Research Institute

Research Area

Dr. An’s research is focused on developing a detailed molecular understanding of regulation of erythropoiesis. Her lab has developed methods to purify both human and mouse erythroid cells at distinct developmental stages and methods to quantify the progress of erythroid differentiation in vivo. Through RNA-seq analysis, her lab constructed global transcriptomesof human and murine erythroid cells. Based on the development of these novel methodology and database, Dr. An’s lab is currently working on three areas: 1) studying regulation of erythropoiesis by epigenetic modifiers such as methylcytosine dioxygenase TET2 and TET3; 2) Identifying the contribution of commonly mutated epigenetic modifiers to the dyserythropoiesis of myelodysplastic syndromes patients; 3) Improving red cell production ex vivo from stem cells.

Contact Information

Email: XAn@nybc.org
Phone: +1 (212) 570-3247

Lab Personnel

  • Xinhua Guo, MS, Senior Research Associate
  • Yaomei Wang, MD, Visiting Scientist, PhD Student
  • Xin Wei, MD, Visiting Scientist
  • Lingdi Zhao, MD, PhD, Visiting Scientist

Funding Support

  • Hugoton Foundation Grant An (PI) 1/1/2018 – 12/31/2018 “Regulation of Human Early Stage Erythropoiesis”

  • NIH R01 HL140625 An, Lobo, Westhoff (Multi-PI) 12/15/2017-11/30/2021 "Use of forward genetic approaches to identify Babesia receptors”

Education and Training

Doctoral Training
MD Henan Medical University, China
PhD in Biochemistry, Tokyo Women’s Medical University, Japan

Post-doctoral Training
Molecular Biology and Cell Biology, Lawrence Berkeley National Laboratory, CA